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Shcheglovitov LabFollow

We study the cellular and molecular basis of human neurodevelopmental disorders #autism #epilepsy using #stemcells #organoids #scRNAseq #ephys @UUNeurobiology🧠

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Alex Shcheglovitov @AlexShcheglovit·

6 Dec

Had a great time at #AES2021 in Chicago. Really enjoyed talks by @SolteszLab and @Newrotrash! Also, it felt really good to present for people in person!

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Alex Shcheglovitov @AlexShcheglovit·

3 Dec

Excited to teach in organoid workshop with @MakinsonLab and @GiorgiaQuadrato @AmEpilepsySoc #AES2021 tonight: https://aes.ims.events/agenda/basic-science-skills-workshop-stem-cell-derived-brain-organoid-approaches-epilepsy-research

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Denis Jabaudon @denisjabaudon·

21 Oct

In 2(!) articles in Nature, Shibita et al from the Sestan lab look at prefrontal cx expansion in humans. Findings: retinoic acid high frontally and affects connect & spines (Paper 1); also, Cbln2 is key to this effect (paper 2). Wow.
Also N&V by @pollen
https://www.nature.com/articles/d41586-021-02460-3

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kartik pattabiraman @kartikpattabir1·

1 Oct

Excited to share our two manuscripts published online today. They are the culmination of almost a decade of work in the Sestan Laboratory. We set out to understand how the human prefrontal cortex acquired its molecular identity and connectivity. https://www.nature.com/articles/s41586-021-03953-x

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Shcheglovitov Lab @shcheglovitov·

1 Oct

In this review published in SI of #Neurotherapeutics on #Epilepsy (@SpringerNature), Randall Peterson (@uofupharmacy) and @AlexShcheglovit discuss how #zebrafish, #iPSC neurons and #organoids could be used for anti-epileptic #drugdiscovery. Read here: https://rdcu.be/cyHBW

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